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dc.contributor.authorGorzalczany, Susana
dc.contributor.authorRosella, Maria A.
dc.contributor.authorSpegazzini, Etile D.
dc.contributor.authorAcevedo, Cristina
dc.contributor.authorDebenedetti, Silvia L.
dc.date.accessioned2014-07-24T18:01:15Z
dc.date.available2014-07-24T18:01:15Z
dc.date.issued2009
dc.identifier.issn0102-695X
dc.identifier.urihttp://repositorio.ub.edu.ar/handle/123456789/2706
dc.description.abstractThe anti-inflammatory activity of the petroleum ether, dichloromethane and methanol extracts from Heterotheca subaxillaris var. latifolia were assayed using 12-O-tetradecanoyl phorbol acetate (TPA) induced ear edema test in mice and carrageenan-induced paw edema test in rats. The dichloromethane extract showed a significant anti-inflammatory activity (91% of inhibition) in TPA-induced ear edema test (topical administration at 1 mg/ear). No effects were seen on carragenan-induced edema. Bio-guided fractionation deal to the isolation of the major flavonoids santin, pectolinaringenin, 3,6-dimethoxy-5,7,4'-trihydroxyflavone and hispidulin present in the active fractions.es_ES
dc.language.isoenes_ES
dc.publisher.EditorUniversidad de Belgrano. Facultad de Ciencias Exactas y Naturales. Proyectos de Investigación
dc.relation.ispartofseriesRevista Brasileira de Farmacognosia;ol.19 no.4 João Pessoa Oct./Dec. 2009
dc.subjectHeterotheca subaxillaris var. latifoliaes_ES
dc.subjectAsteraceaees_ES
dc.subjectanti-inflammatory activityes_ES
dc.subjectflavonoidses_ES
dc.subjectActividad anti-inflamatoria
dc.subjectFlavonoides
dc.titleAnti-inflammatory activity of Heterotheca subaxillaris var. latifolia (Buckley) Gandhi & R.D. Thomas, Asteraceaees_ES
dc.typeArticlees_ES


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