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A facile one-pot synthesis of 8-oxo-7,8-dihydro-(2′-deoxy)adenosine in water
(2006)
Reaction of 2-mercaptoethanol with 8-bromo-2′-deoxyadenosine and 8-bromo-adenosine in aqueous solution and in the presence of triethylamine gave the 8-oxo-adenine derivatives in very good yields. Some mechanistic details ...