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Why modeling? Mathematical models of the human sleep/wake cycle gives new insights on the pathophysiology of fatal familial insomnia (FFI) - Porque fazer modelos? Modelos matemáticos para ciclo de vigília/sono em humanos, fornecem novos insights na fisiopatologia da insônia família fatal (IFF)
(Universidad de Belgrano - Facultad de Ingeniería y Tecnología Informática - Proyectos de Investigación, 2013)FFI, a rare prion disease, constitutes by their wake and sleep abnormalities a unique pathophysiological model of disease. Recently, a neurobiological-mathematical model of the human sleep/ wake cycle (MMSWC) developed ...